Journal Article
An alternative surgical approach: Stem cell conjunctival autograft transplantation following surgical debulking of limbal dermoid

Authors

Abstract

Purpose: This study aims to assess the safety and efficacy of Stem cell conjunctival autograft
transplantation following surgical excision of limbal dermoid as an alternative approach to AMG
transplantation.
Methods: A hospital-based observational study was conducted at a tertiary eye hospital. A total of 35
patients were included in the study. Patients underwent a routine ophthalmological examination at the
follow-up period of 1st POD, 7th POD, 1 month and 3 months along with visual acuity, infection,
corneal scar, and recurrence as degerminators of outcome.
Results: About 34.29% (age group 1-10 years) underwent surgical treatment of limbal dermoid. About
51.43% (n=18) patients were female and 48.57% (n=17) patients were male. Limbal dermoid were
found common in the left eye of 57.14% of the patientsandthe right eye of 42.86% of the patients. Most
of the limbal dermoid grade-I was54.29% and grade-II was 45.71% and this difference was
statistically significant (x2= 39.29, df = 9, Gamma V= .39, Lamda ë = .42). Majority of the patients
(51.43%) had limbal dermoid located in Inferotemporal region (P<0.05). The second most common
location was the supero-temporal region (28.57%). Postoperatively infection was seen in 8%of
patients, corneal structural disfigurement was found in 8%of patients, and recurrence of dermoid was
seen in 4% of the patients.
Conclusion: Combined simple excision with suture-less limbo-conjunctival autograft may be an
alternative approach to AMG transplantation in the surgical treatment of limbal dermoid due to its
good cosmetic and functional outcomes with reduced incidence of recurrence and complication.

Published In:

Ophthalmology Journal

(Volume: 50, Issue : 2)

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Journal of ophthalmological Society of Bangladesh

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